b

Massimo Lopes

l

won

the WBW (Wilhelm Bernhard Workshop) Young investigator award 2017.

He gave the award lecture "Replication fork remodeling: a double-edged sword in genome stability and cancer therapy"
on 22th June at WBW in Nizhny Novgorod, Russia.


Hind Hashwah

hind

won a poster prize at the 7th Cancer Network Zurich Retreat (March 26 - 28, 2017) in Emmetten, Switzerland.


Isabelle Arnold

won one of the Best Workshop Presentation Awards

for her presentation on "Eosinophils function in experimental H. pylori infection" at the World Immune Regulation Meeting (WIRM) in Davos.
 


Anna Stelling

as

received the Charles Rodolphe Brupbacher Young Investigator Award 2017
for her work "Tumor suppressive mechanisms of S1PR2 signaling in DLBCL".


 

Alessandro SARTORI in UZH Journal 6/2016

s

«Der Feind im eigenen Körper»

Matteo Berti and Stanislaw Jozwiakowski were awarded a Marie Skłodowska-Curie Fellowship.

RECENT PUBLICATIONS

Zellweger, Ralph; Lopes, Massimo (2018). Dynamic Architecture of Eukaryotic DNA Replication Forks In Vivo, Visualized by Electron Microscopy In: Muzi-Falconi, Marco; Brown, Grant W. Genome Instability : Methods and Protocols. New York: Springer, 261-294.

Porro, Antonio; Berti, Matteo; Pizzolato, Julia; Bologna, Serena; Kaden, Svenja; Saxer, Anja; Ma, Yue; Nagasawa, Kazuo; Sartori, Alessandro A; Jiricny, Josef (2017). FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2 Nature Communications, 8(1):1073.

Juskevicius, Darius; Müller, Anne; Hashwah, Hind; Lundberg, Pontus; Tzankov, Alexandar; Menter, Thomas (2017). Characterization of the mutational profile of 11 diffuse large B-cell lymphoma cell lines Leukemia & Lymphoma:Epub ahead of print.

Mijic, Sofija; Zellweger, Ralph; Chappidi, Nagaraja; Berti, Matteo; Jacobs, Kurt; Mutreja, Karun; Ursich, Sebastian; Ray Chaudhuri, Arnab; Nussenzweig, Andre; Janscak, Pavel; Lopes, Massimo (2017). Replication fork reversal triggers fork degradation in BRCA2-defective cells Nature Communications, 8(1):859.

Boege, Yannick; Malehmir, Mohsen; Healy, Marc E; Wolf, Monika Julia; Böhm, Friederike; Frick, Lukas; Maire, Renaud; Moch, Holger; Heikenwalder, Mathias; Weber, Achim; et al (2017). A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development. Cancer Cell, 32(3):342-359.e10.

Vujanovic, Marko; Krietsch, Jana; Raso, Maria Chiara; Terraneo, Nastassja; Zellweger, Ralph; Schmid, Jonas A; Taglialatela, Angelo; Huang, Jen-Wei; Holland, Cory L; Zwicky, Katharina; Herrador, Raquel; Jacobs, Heinz; Cortez, David; Ciccia, Alberto; Penengo, Lorenza; Lopes, Massimo (2017). Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity. Molecular Cell, 67(5):882-890.e5.

Hashwah, Hind; Schmid, Corina A; Kasser, Sabrina; Bertram, Katrin; Stelling, Anna; Manz, Markus G; Müller, Anne (2017). Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth. Proceedings of the National Academy of Sciences of the United States of America, 114(36):9701-9706.

Kyburz, Andreas; Urban, Sabine; Altobelli, Aleksandra; Floess, Stefan; Huehn, Jochen; Cover, Timothy L; Müller, Anne (2017).Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy. Clinical and Experimental Allergy:Epub ahead of print.

Takizawa, Hitoshi; Fritsch, Kristin; Kovtonyuk, Larisa V; Saito, Yasuyuki; Yakkala, Chakradhar; Jacobs, Kurt; Ahuja, Akshay K; Lopes, Massimo; Hausmann, Annika; Hardt, Wolf-Dietrich; Gomariz, Álvaro; Nombela-Arrieta, César; Manz, Markus G (2017). Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness. Cell Stem Cell, 21(2):225-240.e5.

Graf, Urs; Casanova, Elisa A; Wyck, Sarah; Dalcher, Damian; Gatti, Marco; Vollenweider, Eva; Okoniewski, Michal J; Weber, Fabienne A; Patel, Sameera S; Schmid, Marc W; Li, Jiwen; Sharif, Jafar; Wanner, Guido A; Koseki, Haruhiko; Wong, Jiemin; Pelczar, Pawel; Penengo, Lorenza; Santoro, Raffaella; Cinelli, Paolo (2017). Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways. Nature Cell Biology, 19(7):763-773.

Di Marco, Stefano; Hasanova, Zdenka; Kanagaraj, Radhakrishnan; Chappidi, Nagaraja; Altmannova, Veronika; Menon, Shruti; Sedlackova, Hana; Langhoff, Jana; Surendranath, Kalpana; Hühn, Daniela; Bhowmick, Rahul; Marini, Victoria; Ferrari, Stefano; Hickson, Ian D; Krejci, Lumir; Janscak, Pavel (2017). RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Molecular Cell, 66(5):658-671.e8.