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Janscak Lab
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ZORA Publication List
Publications
2024
Journal Article
Martinikova, A. S., Stoyanov, M., Oravetzova, A., Kok, Y. P., Yu, S., Dobrovolna, J., Janscak, P., van Vugt, M., & Macurek, L. (2024).
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression
Molecular Oncology, 18, 6–20. https://doi.org/10.1002/1878-0261.13433
2020
Journal Article
Bauer, M., Nascakova, Z., Mihai, A.-I., Cheng, P. F., Levesque, M. P., Lampart, S., Hurwitz, R., Pfannkuch, L., Dobrovolna, J., Jacobs, M., Bartfeld, S., Dohlman, A., Shen, X., Gall, A. A., Salama, N. R., Töpfer, A., Weber, A., Meyer, T. F., Janscak, P., & Müller, A. (2020).
The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress
Nature Communications, 11, 5117. https://doi.org/10.1038/s41467-020-18857-z
2013
Journal Article
Steger, M., Murina, O., Hühn, D., Ferretti, L. P., Walser, R., Hänggi, K., Lafranchi, L., Neugebauer, C., Paliwal, S., Janscak, P., Gerrits, B., Del Sal, G., Zerbe, O., & Sartori, A. A. (2013).
Prolyl isomerase PIN1 regulates DNA double-strand break repair by Counteracting DNA end resection
Molecular Cell, 50, 333–343. https://doi.org/10.1016/j.molcel.2013.03.023
2010
Journal Article
Schwendener, S., Raynard, S., Paliwal, S., Cheng, A., Kanagaraj, R., Shevelev, I., Stark, J. M., Sung, P., & Janscak, P. (2010).
Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity
Journal of Biological Chemistry, 285, 15739–15745. https://doi.org/10.1074/jbc.M110.110478
2008
Journal Article
Ren, H., Dou, S. X., Zhang, X. D., Wang, P. Y., Kanagaraj, R., Liu, J. L., Janscak, P., Hu, J. S., & Xi, X. G. (2008).
The zinc-binding motif of human RECQ5beta suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme
Biochemical Journal, 412, 425–433. https://doi.org/10.1042/BJ20071150
2007
Journal Article
Saydam, N., Kanagaraj, R., Dietschy, T., Garcia, P. L., Peña-Diaz, J., Shevelev, I., Stagljar, I., & Janscak, P. (2007).
Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors
Nucleic Acids Research, 35, 5706–5716. https://doi.org/10.1093/nar/gkm500
Hu, Y., Raynard, S., Sehorn, M. G., Lu, X., Bussen, W., Zheng, L., Stark, J. M., Barnes, E. L., Chi, P., Janscak, P., Jasin, M., Vogel, H., Sung, P., & Luo, G. (2007).
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments
Genes and Development, 21, 3073–3084. https://doi.org/10.1101/gad.1609107
2006
Journal Article
Kanagaraj, R., Saydam, N., Garcia, P. L., Zheng, L., & Janscak, P. (2006).
Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork
Nucleic Acids Research, 34, 5217–5231. https://doi.org/10.1093/nar/gkl677
2005
Journal Article
Cheok, C. F., Wu, L., Garcia, P. L., Janscak, P., & Hickson, I. D. (2005).
The Bloom’s syndrome helicase promotes the annealing of complementary single-stranded DNA. Nucleic Acids Research, 33, 3932–3941.
https://doi.org/10.1093/nar/gki712
Wu, L., Chan, K. L., Ralf, C., Bernstein, D. A., Garcia, P. L., Bohr, V., Vindigni, A., Janscak, P., Keck, J. L., & Hickson, I. D. (2005).
The HRDC domain of BLM is required for the dissolution of double Holliday junctions
The EMBO Journal, 24, 2679–2687. https://doi.org/10.1038/sj.emboj.7600740
2004
Journal Article
Garcia, P. L., Liu, Y., Jiricny, J., West, S. C., & Janscak, P. (2004).
Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide
The EMBO Journal, 23, 2882–2891. https://doi.org/10.1038/sj.emboj.7600301
Garcia, P. L., Bradley, G., Hayes, C. H., Krintel, S. J., Soultanas, P., & Janscak, P. (2004).
RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases
Nucleic Acids Research, 32, 3771–3778. https://doi.org/10.1093/nar/gkh709
2003
Journal Article
Janscak, P., Garcia, P. L., Hamburger, F., Makuta, Y., Shiraishi, K., Imai, Y., Ikeda, H., & Bickle, T. A. (2003).
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
Journal of Molecular Biology, 330, 29–42. https://doi.org/10.1016/S0022-2836(03)00534-5