Kristin Stirm

Kristin Stirm

PhD Student


 

During my Bachelor studies of Biomedical Sciences, I was working as a student trainee on ovarian cancer biomarker discovery at the Natural and Medical Sciences Institute at the University of Tübingen. At the SciLifeLab in Stockholm I pursued my Bachelor thesis, which was followed by a six-months industry internship at Roche in Penzberg, Bavaria in the field of immunology. Thereafter, I studied Molecular Biosciences, Major Cancer Biology at the University of Heidelberg and the German Cancer Research Center (DKFZ), where I had the great opportunity to broaden my scientific experience during a research stay at the Weizmann Institute of Science in Rehovot, Israel in the group of Prof. Idit Shachar. While investigating the role of SLAMF9 in chronic lymphocytic leukemia at the Weizmann Institute, I sharpened my passion for tumor immunology, which I was eager to harness during my Master thesis at the DKFZ in the group of Prof. Mathias Heikenwälder. Dealing with the immune checkpoint PD-L1 in murine NASH-to-HCC transition required comprehensive CRISPR/Cas9 and shRNA-based genetic in-vivo manipulation strategies, which I was fascinated to exploit. Afterwards, I was thrilled to pursue my PhD studies at the IMCR under the supervision of Prof. Anne Müller, where I am currently deciphering a dual role of tumor cell-derived IL-10 in promoting cell-autonomous growth and immune escape in diffuse large B-cell lymphoma with special focus on regulatory T-cells. Outside of the lab, I love traveling, sailing, several other outdoor sports as well as music and multi-cultural food.