UZH - Institute of Molecular Cancer Research

Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF–IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of Experimental Medicine, 217(12):e20190706.
Walser, Franziska; Mulder, Monique P C; Bragantini, Benoît; Burger, Sibylle; Gubser, Tatiana; Gatti, Marco; Botuyan, Maria Victoria; Villa, Alessandra; Altmeyer, Matthias; Neri, Dario; Ovaa, Huib; Mer, Georges; Penengo, Lorenza (2020). Ubiquitin phosphorylation at Thr12 modulates the DNA damage response. Molecular Cell, 80(3):423-436.e9.
Bassi, Gabriele; Favalli, Nicholas; Vuk, Miriam; Catalano, Marco; Martinelli, Adriano; Trenner, Anika; Porro, Antonio; Yang, Su; Tham, Chuin Lean; Moroglu, Mustafa; Yue, Wyatt W; Conway, Stuart J; Vogt, Peter K; Sartori, Alessandro A; Scheuermann, Jörg; Neri, Dario (2020). A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks. Advanced Science, 7(22):2001970.
Rubbiani, Riccardo; Wu, Wenyu; Naik, Anu; Larocca, Michele; Schneider, Lukas; Padrutt, Roxane; Babu, Vipin; König, Christiane; Hinger, Doris; Maake, Caroline; Ferrari, Stefano; Gasser, Gilles; Spingler, Bernhard (2020). Studying the cellular distribution of highly phototoxic platinated metalloporphyrins using isotope labelling. Chemical Communications, 56(92):14373-14376.
Bauer, Michael; Nascakova, Zuzana; Mihai, Anca-Irina; Cheng, Phil F; Levesque, Mitchell P; Lampart, Simon; Hurwitz, Robert; Pfannkuch, Lennart; Dobrovolna, Jana; Jacobs, Melanie; Bartfeld, Sina; Dohlman, Anders; Shen, Xiling; Gall, Alevtina A; Salama, Nina R; Töpfer, Antonia; Weber, Achim; Meyer, Thomas F; Janscak, Pavel; Müller, Anne (2020). The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress. Nature Communications, 11(1):5117.
Zhang, Xiaozhou; Artola-Boran, Mariela; Fallegger, Angela; Arnold, Isabelle C; Weber, Achim; Reuter, Sebastian; Taube, Christian; Müller, Anne (2020). IRF4 Expression Is Required for the Immunoregulatory Activity of Conventional Type 2 Dendritic Cells in Settings of Chronic Bacterial Infection and Cancer. Journal of Immunology, 205(7):1933-1943.
Cannavo, Elda; Sanchez, Aurore; Anand, Roopesh; Ranjha, Lepakshi; Hugener, Jannik; Adam, Céline; Acharya, Ananya; Weyland, Nicolas; Aran-Guiu, Xavier; Charbonnier, Jean-Baptiste; Hoffmann, Eva R; Borde, Valérie; Matos, Joao; Cejka, Petr (2020). Regulation of the MLH1-MLH3 endonuclease in meiosis. Nature, 586(7830):618-622.
Berti, Matteo; Cortez, David; Lopes, Massimo (2020). The plasticity of DNA replication forks in response to clinically relevant genotoxic stress. Nature Reviews. Molecular Cell Biology, 21(10):633-651.
Mozaffari, Nour L; Pagliarulo, Fabio; Sartori, Alessandro A (2020). Human CtIP: A 'double agent' in DNA repair and tumorigenesis. Seminars in Cell & Developmental Biology:Epub ahead of print.
Francica, Paola; Mutlu, Merve; Blomen, Vincent A; Oliveira, Catarina; Nowicka, Zuzanna; Trenner, Anika; Gerhards, Nora M; Bouwman, Peter; Stickel, Elmer; Hekkelman, Maarten L; Lingg, Lea; Klebic, Ismar; van de Ven, Marieke; de Korte-Grimmerink, Renske; Howald, Denise; Jonkers, Jos; Sartori, Alessandro A; Fendler, Wojciech; Chapman, J Ross; Brummelkamp, Thijn; Rottenberg, Sven (2020). Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining. Cell Reports, 32(8):108068.
Rainey, Michael D; Quinlan, Aisling; Cazzaniga, Chiara; Mijic, Sofija; Martella, Oliviano; Krietsch, Jana; Göder, Anja; Lopes, Massimo; Santocanale, Corrado (2020). CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage. EMBO Reports, 21(8):e48920.
Raso, Maria Chiara; Djoric, Nikola; Walser, Franziska; Hess, Sandra; Schmid, Fabian Marc; Burger, Sibylle; Knobeloch, Klaus-Peter; Penengo, Lorenza (2020). Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage. Journal of Cell Biology, 219(8):1-21.
Berti, Matteo; Teloni, Federico; Mijic, Sofija; Ursich, Sebastian; Fuchs, Jevgenij; Palumbieri, Maria Dilia; Krietsch, Jana; Schmid, Jonas A; Garcin, Edwige B; Gon, Stéphanie; Modesti, Mauro; Altmeyer, Matthias; Lopes, Massimo (2020). Sequential role of RAD51 paralog complexes in replication fork remodeling and restart. Nature Communications, 11(1):3531.
Mariotti, Laura; Wild, Sebastian; Brunoldi, Giulia; Piceni, Alessandra; Ceppi, Ilaria; Kummer, Sandra; Lutz, Richard E; Cejka, Petr; Gari, Kerstin (2020). The iron-sulphur cluster in human DNA2 is required for all biochemical activities of DNA2. Communications Biology, 3(1):322.
Bai, Gongshi; Kermi, Chames; Stoy, Henriette; Schiltz, Carl J; Bacal, Julien; Zaino, Angela M; Hadden, M Kyle; Eichman, Brandt F; Lopes, Massimo; Cimprich, Karlene A (2020). HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis. Molecular Cell, 78(6):1237-1251.e7.
Orjuela, Stephany; Machlab, Dania; Menigatti, Mirco; Marra, Giancarlo; Robinson, Mark D (2020). DAMEfinder: a method to detect differential allele-specific methylation. Epigenetics & Chromatin, 13:25.
Odermatt, Diana C; Lee, Wei Ting C; Wild, Sebastian; Jozwiakowski, Stanislaw K; Rothenberg, Eli; Gari, Kerstin (2020). Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolism. PLoS Genetics, 16(6):e1008740.
Bahar Halpern, Keren; Massalha, Hassan; Zwick, Rachel K; Moor, Andreas E; Castillo-Azofeifa, David; Rozenberg, Milena; Farack, Lydia; Egozi, Adi; Miller, Dan R; Averbukh, Inna; Harnik, Yotam; Weinberg-Corem, Noa; de Sauvage, Frederic J; Amit, Ido; Klein, Ophir D; Shoshkes-Carmel, Michal; Itzkovitz, Shalev (2020). Lgr5+ telocytes are a signaling source at the intestinal villus tip. Nature Communications, 11:1936.
Ceppi, Ilaria; Howard, Sean M; Kasaciunaite, Kristina; Pinto, Cosimo; Anand, Roopesh; Seidel, Ralf; Cejka, Petr (2020). CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection. Proceedings of the National Academy of Sciences of the United States of America, 117(16):8859-8869.
Gerlach, Magdalena M; Stelling-Germani, Anna; Wu, Cheuk Ting; Newrzela, Sebastian; Döring, Claudia; Vela, Visar; Müller, Anne; Hartmann, Sylvia; Tzankov, Alexandar (2020). SMAD1 promoter hypermethylation and lack of SMAD1 expression in Hodgkin lymphoma: a potential target for hypomethylating drug therapy. Haematologica, 106(2):619-621.

Fusszeile