Bauer, Michael; Nascakova, Zuzana; Mihai, Anca-Irina; Cheng, Phil F; Levesque, Mitchell P; Lampart, Simon; Hurwitz, Robert; Pfannkuch, Lennart; Dobrovolna, Jana; Jacobs, Melanie; Bartfeld, Sina; Dohlman, Anders; Shen, Xiling; Gall, Alevtina A; Salama, Nina R; Töpfer, Antonia; Weber, Achim; Meyer, Thomas F; Janscak, Pavel; Müller, Anne (2020). The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress. Nature Communications, 11(1):5117. Zhang, Xiaozhou; Artola-Boran, Mariela; Fallegger, Angela; Arnold, Isabelle C; Weber, Achim; Reuter, Sebastian; Taube, Christian; Müller, Anne (2020). IRF4 Expression Is Required for the Immunoregulatory Activity of Conventional Type 2 Dendritic Cells in Settings of Chronic Bacterial Infection and Cancer. Journal of Immunology, 205(7):1933-1943. Berti, Matteo; Cortez, David; Lopes, Massimo (2020). The plasticity of DNA replication forks in response to clinically relevant genotoxic stress. Nature Reviews. Molecular Cell Biology, 21(10):633-651. Mozaffari, Nour L; Pagliarulo, Fabio; Sartori, Alessandro A (2020). Human CtIP: A 'double agent' in DNA repair and tumorigenesis. Seminars in Cell & Developmental Biology:Epub ahead of print. Francica, Paola; Mutlu, Merve; Blomen, Vincent A; Oliveira, Catarina; Nowicka, Zuzanna; Trenner, Anika; Gerhards, Nora M; Bouwman, Peter; Stickel, Elmer; Hekkelman, Maarten L; Lingg, Lea; Klebic, Ismar; van de Ven, Marieke; de Korte-Grimmerink, Renske; Howald, Denise; Jonkers, Jos; Sartori, Alessandro A; Fendler, Wojciech; Chapman, J Ross; Brummelkamp, Thijn; Rottenberg, Sven (2020). Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining. Cell Reports, 32(8):108068. Rainey, Michael D; Quinlan, Aisling; Cazzaniga, Chiara; Mijic, Sofija; Martella, Oliviano; Krietsch, Jana; Göder, Anja; Lopes, Massimo; Santocanale, Corrado (2020). CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage. EMBO Reports, 21(8):Epub ahead of print. Raso, Maria Chiara; Djoric, Nikola; Walser, Franziska; Hess, Sandra; Schmid, Fabian Marc; Burger, Sibylle; Knobeloch, Klaus-Peter; Penengo, Lorenza (2020). Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage. Journal of Cell Biology, 219(8):1-21. Berti, Matteo; Teloni, Federico; Mijic, Sofija; Ursich, Sebastian; Fuchs, Jevgenij; Palumbieri, Maria Dilia; Krietsch, Jana; Schmid, Jonas A; Garcin, Edwige B; Gon, Stéphanie; Modesti, Mauro; Altmeyer, Matthias; Lopes, Massimo (2020). Sequential role of RAD51 paralog complexes in replication fork remodeling and restart. Nature Communications, 11(1):3531. Mariotti, Laura; Wild, Sebastian; Brunoldi, Giulia; Piceni, Alessandra; Ceppi, Ilaria; Kummer, Sandra; Lutz, Richard E; Cejka, Petr; Gari, Kerstin (2020). The iron-sulphur cluster in human DNA2 is required for all biochemical activities of DNA2. Communications Biology, 3(1):322. Bai, Gongshi; Kermi, Chames; Stoy, Henriette; Schiltz, Carl J; Bacal, Julien; Zaino, Angela M; Hadden, M Kyle; Eichman, Brandt F; Lopes, Massimo; Cimprich, Karlene A (2020). HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis. Molecular Cell, 78(6):1237-1251.e7. Orjuela, Stephany; Machlab, Dania; Menigatti, Mirco; Marra, Giancarlo; Robinson, Mark D (2020). DAMEfinder: a method to detect differential allele-specific methylation. Epigenetics & Chromatin, 13:25. Odermatt, Diana C; Lee, Wei Ting C; Wild, Sebastian; Jozwiakowski, Stanislaw K; Rothenberg, Eli; Gari, Kerstin (2020). Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolism. PLoS Genetics, 16(6):e1008740. Orjuela, Stephany; Menigatti, Mirco; Schraml, Peter; Kambakamba, Patryk; Robinson, Mark D; Marra, Giancarlo (2020). The DNA hypermethylation phenotype of colorectal cancer liver metastases resembles that of the primary colorectal cancers. BMC Cancer, 20:290. Ragusa, Simone; Prat-Luri, Borja; González-Loyola, Alejandra; Nassiri, Sina; Squadrito, Mario Leonardo; Guichard, Alan; Cavin, Sabrina; Gjorevski, Nikolce; Barras, David; Marra, Giancarlo; Lutolf, Matthias P; Perentes, Jean; Corse, Emily; Bianchi, Roberta; Wetterwald, Laureline; Kim, Jaeryung; Oliver, Guillermo; Delorenzi, Mauro; De Palma, Michele; Petrova, Tatiana V (2020). Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice. Journal of Clinical Investigation, 130(3):1199-1216. Andrs, Martin; Hasanova, Zdenka; Oravetzova, Anna; Dobrovolna, Jana; Janscak, Pavel (2020). RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription. Genes, 11(2):232. Simon, Anna K; Kummer, Sandra; Wild, Sebastian; Lezaja, Aleksandra; Teloni, Federico; Jozwiakowski, Stanislaw K; Altmeyer, Matthias; Gari, Kerstin (2020). The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation. Life Science Alliance, 3(3):e201900547. Chappidi, Nagaraja; Nascakova, Zuzana; Boleslavska, Barbora; Zellweger, Ralph; Isik, Esin; Andrs, Martin; Menon, Shruti; Dobrovolna, Jana; Balbo Pogliano, Chiara; Matos, Joao; Porro, Antonio; Lopes, Massimo; Janscak, Pavel (2020). Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops. Molecular Cell, 77(3):528-541.e8.
