Publications

ZORA Publication List

Publications

• 2025

  • Journal Article

    • Duzanic, F., Mohana-Natarajan, V., Fisicaro, S., Bakker, C., Aouami, M., Amaral, G., Lopes, M., Taneja, N., & Penengo, L. (2025). H2BK120ub and its reader RNF169 sequentially regulate replication fork remodeling and stability The EMBO Journal, 44, 6598–6625. https://doi.org/10.1038/s44318-025-00602-1
    • Duzanic, F. D., & Penengo, L. (2025). The interferon response at the intersection of genome integrity and innate immunity DNA Repair, 145, 103786. https://doi.org/10.1016/j.dnarep.2024.103786

  • Dissertation

    • Duzanic, F. (2025). Exploring the Roles of Post Translational Modifications in the DNA Replication Fork Dynamics and Protection (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-278137
    • Stavrou, M. (2025). The Role of Ubiquitin Phosphorylation in Genome Stability (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-278141
    • Collotta, G. (2025). Defining Molecular Mechanisms Regulating FAN1 Protein Stability (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-270791

• 2023

  • Journal Article

    • Moro, R. N., Biswas, U., Kharat, S. S., Duzanic, F. D., Das, P., Stavrou, M., Raso, M. C., Freire, R., Chaudhuri, A. R., Sharan, S. K., & Penengo, L. (2023). Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15 Nature Communications, 14, 6140. https://doi.org/10.1038/s41467-023-41801-w

• 2021

  • Journal Article

    • Mattiroli, F., & Penengo, L. (2021). Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability Trends in Genetics : Tig, 37, 566–581. https://doi.org/10.1016/j.tig.2020.12.005

• 2020

  • Journal Article

    • Walser, F., Mulder, M. P. C., Bragantini, B., Burger, S., Gubser, T., Gatti, M., Botuyan, M. V., Villa, A., Altmeyer, M., Neri, D., Ovaa, H., Mer, G., & Penengo, L. (2020). Ubiquitin phosphorylation at Thr12 modulates the DNA damage response Molecular Cell, 80, 423-436.e9. https://doi.org/10.1016/j.molcel.2020.09.017
    • Raso, M. C., Djoric, N., Walser, F., Hess, S., Schmid, F. M., Burger, S., Knobeloch, K.-P., & Penengo, L. (2020). Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage Journal of Cell Biology, 219, 1–21. https://doi.org/10.1083/jcb.202002175
    • Okonska, A., Bühler, S., Rao, V., Ronner, M., Blijlevens, M., van der Meulen-Muileman, I. H., de Menezes, R. X., Wipplinger, M., Oehl, K., Smit, E. F., Weder, W., Stahel, R. A., Penengo, L., van Beusechem, V. W., & Felley-Bosco, E. (2020). Functional genomic screen in mesothelioma reveals that loss of function of BRCA1-associated-protein-1 induces chemoresistance to ribonucleotide reductase inhibition Molecular Cancer Therapeutics, 19, 552–563. https://doi.org/10.1158/1535-7163.MCT-19-0356

• 2018

  • Journal Article

    • Squarzanti, D. F., Sorrentino, R., Landini, M. M., Chiesa, A., Pinato, S., Rocchio, F., Mattii, M., Penengo, L., & Azzimonti, B. (2018). Human papillomavirus type 16 E6 and E7 oncoproteins interact with the nuclear p53-binding protein 1 in an in vitro reconstructed 3D epithelium: new insights for the virus-induced DNA damage response Virology Journal, 15, 176. https://doi.org/10.1186/s12985-018-1086-4
    • Schmid, J. A., Berti, M., Walser, F., Raso, M. C., Schmid, F., Krietsch, J., Stoy, H., Zwicky, K., Ursich, S., Freire, R., Lopes, M., & Penengo, L. (2018). Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase Molecular Cell, 71, 897-910.e8. https://doi.org/10.1016/j.molcel.2018.07.011

  • Dissertation

    • Himmels, S.-F. (2018). Characterization of molecular networks governing CtlP ubiquitination (Dissertation, University of Zurich)

• 2017

  • Journal Article

    • Balbo Pogliano, C., Gatti, M., Rüthemann, P., Garajovà, Z., Penengo, L., & Naegeli, H. (2017). ASH1L histone methyltransferase regulates the handoff between damage recognition factors in global-genome nucleotide excision repair Nature Communications, 8, 1333. https://doi.org/10.1038/s41467-017-01080-8
    • Vujanovic, M., Krietsch, J., Raso, M. C., Terraneo, N., Zellweger, R., Schmid, J. A., Taglialatela, A., Huang, J.-W., Holland, C. L., Zwicky, K., Herrador, R., Jacobs, H., Cortez, D., Ciccia, A., Penengo, L., & Lopes, M. (2017). Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity Molecular Cell, 67, 882-890.e5. https://doi.org/10.1016/j.molcel.2017.08.010
    • Graf, U., Casanova, E. A., Wyck, S., Dalcher, D., Gatti, M., Vollenweider, E., Okoniewski, M. J., Weber, F. A., Patel, S. S., Schmid, M. W., Li, J., Sharif, J., Wanner, G. A., Koseki, H., Wong, J., Pelczar, P., Penengo, L., Santoro, R., & Cinelli, P. (2017). Corrigendum: Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways Nature Cell Biology, 19, 1003. https://doi.org/10.1038/ncb3572
    • Graf, U., Casanova, E. A., Wyck, S., Dalcher, D., Gatti, M., Vollenweider, E., Okoniewski, M. J., Weber, F. A., Patel, S. S., Schmid, M. W., Li, J., Sharif, J., Wanner, G. A., Koseki, H., Wong, J., Pelczar, P., Penengo, L., Santoro, R., & Cinelli, P. (2017). Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways Nature Cell Biology, 19, 763–773. https://doi.org/10.1038/ncb3554
    • Parrotta, R., Okonska, A., Ronner, M., Weder, W., Stahel, R., Penengo, L., & Felley-Bosco, E. (2017). A novel BRCA1-associated protein-1 isoform affects response of mesothelioma cells to drugs impairing BRCA1-mediated DNA repair Journal of Thoracic Oncology, 12, 1309–1319. https://doi.org/10.1016/j.jtho.2017.03.023

  • Dissertation

    • Codilupi, T. (2017). CRL4 ubiquitin ligase promotes fanconi anemia pathway-induced single-stranded DNA signaling at interstrand crosslinks (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-205100

• 2015

  • Journal Article

    • Gatti, M., Pinato, S., Maiolica, A., Rocchio, F., Prato, M. G., Aebersold, R., & Penengo, L. (2015). RNF168 promotes noncanonical K27 ubiquitination to signal DNA damage Cell Reports, 10, 226–238. https://doi.org/10.1016/j.celrep.2014.12.021

Pagination