Publications

ZORA Publication List

Publications

• 2024

  • Journal Article

    • Rao, Satyajeet; Andrs, Martin; Shukla, Kaustubh; Isik, Esin; König, Christiane; Schneider, Stefan; Bauer, Michael; Rosano, Vinicio; Prokes, Jiri; Müller, Anne; Janscak, Pavel (2024). Senataxin RNA/DNA helicase promotes replication restart at co-transcriptional R-loops to prevent MUS81-dependent fork degradation. Nucleic Acids Research, 52(17):10355-10369.
    • Martinikova, Andra S; Stoyanov, Miroslav; Oravetzova, Anna; Kok, Yannick P; Yu, Shibo; Dobrovolna, Jana; Janscak, Pavel; van Vugt, Marcel; Macurek, Libor (2024). PPM1D activity promotes the replication stress caused by cyclin E1 overexpression. Molecular Oncology, 18(1):6-20.

• 2023

  • Journal Article

    • Andrs, Martin; Stoy, Henriette; Boleslavska, Barbora; Chappidi, Nagaraja; Kanagaraj, Radhakrishnan; Nascakova, Zuzana; Menon, Shruti; Rao, Satyajeet; Oravetzova, Anna; Dobrovolna, Jana; Surendranath, Kalpana; Lopes, Massimo; Janscak, Pavel (2023). Excessive reactive oxygen species induce transcription-dependent replication stress. Nature Communications, 14(1):1791.
    • Han, Zhe; Andrs, Martin; Madhavan, Bindhu K; Kaymak, Serap; Sulaj, Alba; Kender, Zoltan; Kopf, Stefan; Kihm, Lars; Pepperkok, Rainer; Janscak, Pavel; Nawroth, Peter; Kumar, Varun (2023). The importance of nuclear RAGE-Mcm2 axis in diabetes or cancer-associated replication stress. Nucleic Acids Research, 51(5):2298-2318.

• 2022

  • Journal Article

    • Boleslavska, Barbora; Oravetzova, Anna; Shukla, Kaustubh; Nascakova, Zuzana; Ibini, Oluwakemi Ngozi; Hasanova, Zdenka; Andrs, Martin; Kanagaraj, Radhakrishnan; Dobrovolna, Jana; Janscak, Pavel (2022). DDX17 helicase promotes resolution of R-loop-mediated transcription-replication conflicts in human cells. Nucleic Acids Research, 50(21):12274-12290.
    • Larsen, Brian D; Benada, Jan; Yung, Philip Yuk Kwong; Bell, Ryan A V; Pappas, George; Urban, Vaclav; Ahlskog, Johanna K; Kuo, Tia T; Janscak, Pavel; Megeney, Lynn A; Elsässer, Simon J; Bartek, Jiri; Sørensen, Claus S (2022). Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress. Science, 376(6592):476-483.
    • Sakellariou, Despoina; Bak, Sara Thornby; Isik, Esin; Barroso, Sonia I; Porro, Antonio; Aguilera, Andrés; Bartek, Jiri; Janscak, Pavel; Peña-Diaz, Javier (2022). MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells. Cell Reports, 39(1):110602.

• 2021

  • Journal Article

    • Nascakova, Zuzana; Boleslavska, Barbora; Urban, Vaclav; Oravetzova, Anna; Vlachova, Edita; Janscak, Pavel; Dobrovolna, Jana (2021). RAD51 Inhibition Induces R-Loop Formation in Early G1 Phase of the Cell Cycle. International Journal of Molecular Sciences, 22(7):3740.

• 2020

  • Journal Article

    • Bauer, Michael; Nascakova, Zuzana; Mihai, Anca-Irina; Cheng, Phil F; Levesque, Mitchell P; Lampart, Simon; Hurwitz, Robert; Pfannkuch, Lennart; Dobrovolna, Jana; Jacobs, Melanie; Bartfeld, Sina; Dohlman, Anders; Shen, Xiling; Gall, Alevtina A; Salama, Nina R; Töpfer, Antonia; Weber, Achim; Meyer, Thomas F; Janscak, Pavel; Müller, Anne (2020). The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress. Nature Communications, 11(1):5117.
    • Andrs, Martin; Hasanova, Zdenka; Oravetzova, Anna; Dobrovolna, Jana; Janscak, Pavel (2020). RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription. Genes, 11(2):232.
    • Chappidi, Nagaraja; Nascakova, Zuzana; Boleslavska, Barbora; Zellweger, Ralph; Isik, Esin; Andrs, Martin; Menon, Shruti; Dobrovolna, Jana; Balbo Pogliano, Chiara; Matos, Joao; Porro, Antonio; Lopes, Massimo; Janscak, Pavel (2020). Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops. Molecular Cell, 77(3):528-541.e8.

• 2019

  • Journal Article

    • Teloni, Federico; Michelena, Jone; Lezaja, Aleksandra; Kilic, Sinan; Ambrosi, Christina; Menon, Shruti; Dobrovolna, Jana; Imhof, Ralph; Janscak, Pavel; Baubec, Tuncay; Altmeyer, Matthias (2019). Efficient pre-mRNA cleavage prevents replication-stress-associated genome instability. Molecular Cell, 73(4):670-683.e12.

• 2017

  • Journal Article

    • Mijic, Sofija; Zellweger, Ralph; Chappidi, Nagaraja; Berti, Matteo; Jacobs, Kurt; Mutreja, Karun; Ursich, Sebastian; Ray Chaudhuri, Arnab; Nussenzweig, Andre; Janscak, Pavel; Lopes, Massimo (2017). Replication fork reversal triggers fork degradation in BRCA2-defective cells. Nature Communications, 8:859.
    • Di Marco, Stefano; Hasanova, Zdenka; Kanagaraj, Radhakrishnan; Chappidi, Nagaraja; Altmannova, Veronika; Menon, Shruti; Sedlackova, Hana; Langhoff, Jana; Surendranath, Kalpana; Hühn, Daniela; Bhowmick, Rahul; Marini, Victoria; Ferrari, Stefano; Hickson, Ian D; Krejci, Lumir; Janscak, Pavel (2017). RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Molecular Cell, 66(5):658-671.e8.
    • Henrich, Sarah Marie; Usadel, Clemens; Werwein, Eugen; Burdova, Kamila; Janscak, Pavel; Ferrari, Stefano; Hess, Daniel; Klempnauer, Karl-Heinz (2017). Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling. Scientific Reports, 7:41663.
    • Urban, Vaclav; Dobrovolna, Jana; Janscak, Pavel (2017). Distinct functions of human RecQ helicases during DNA replication. Biophysical Chemistry, 225:20-26.

• 2016

  • Journal Article

    • Piwko, Wojciech; Mlejnkova, Lucie J; Mutreja, Karun; Ranjha, Lepakshi; Stafa, Diana; Smirnov, Alexander; Brodersen, Mia M L; Zellweger, Ralph; Sturzenegger, Andreas; Janscak, Pavel; Lopes, Massimo; Peter, Matthias; Cejka, Petr (2016). The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress. The EMBO Journal, 35:2584-2601.
    • Urban, Vaclav; Dobrovolna, Jana; Hühn, Daniela; Fryzelkova, Jana; Bartek, Jiri; Janscak, Pavel (2016). RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells. Journal of Cell Biology, 214(4):401-415.
    • Budhathoki, Jagat B; Maleki, Parastoo; Roy, William A; Janscak, Pavel; Yodh, Jaya G; Balci, Hamza (2016). A comparative study of g-quadruplex unfolding and DNA reeling activities of human RECQ5 helicase. Biophysical Journal, 110(12):2585-2596.

• 2015

  • Journal Article

    • Burdova, Kamila; Mihaljevic, Boris; Sturzenegger, Andreas; Chappidi, Nagaraja; Janscak, Pavel (2015). The Mismatch-Binding Factor MutSβ Can Mediate ATR Activation in Response to DNA Double-Strand Breaks. Molecular Cell, 59(4):603-614.

Pagination